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The sympathetic nervous system stimulates anti-inflammatory B cells in collagen-type II-induced arthritis

Pongratz, Georg, Melzer, Madlen and Straub, Rainer H. (2012) The sympathetic nervous system stimulates anti-inflammatory B cells in collagen-type II-induced arthritis. Annals of the Rheumatic Diseases (ARD) 71, pp. 432-439.

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Abstract

Background: As previously shown, the sympathetic nervous system (SNS) shows proinflammatory activity during initiation of arthritis but is anti-inflammatory in established collagen-induced arthritis (CIA). Interleukin 10 (IL-10)-producing B cells suppress arthritis and are a potential target of the SNS because (1) B cells express functional β2-adrenoceptors (β2ARs) and (2) IL-10, at least in ...

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Item type:Article
Date:2012
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1136/ard.2011.153056DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:36139
Owner only: item control page

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