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Lipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function

Sigrüner, Alexander, Wolfrum, Christian, Boettcher, Alfred, Kopf, Thomas, Liebisch, Gerhard , Orsó, Evelyn and Schmitz, Gerd (2017) Lipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function. PLoS ONE 12 (5), e0178368.

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Date of publication of this fulltext: 04 Sep 2017 10:08

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178368

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Abstract

Background Sequence variants near the human gene for P4-type ATPase, class V, type 10D (ATP10D) were shown to significantly associate with circulating hexosylceramide d18:1/16:0 and d18:1/24:1 levels, obesity, insulin resistance, plasma high density lipoprotein (HDL), coronary stenotic index and intracranial atherosclerotic index. In mice Atp10d is associated with HDL modulation and C57BL/6 mice ...

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Item type:Article
Date:25 May 2017
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0178368DOI
PONE-D-16-31619Other
Keywords:TANDEM MASS-SPECTROMETRY; HIGH-THROUGHPUT QUANTIFICATION; GENETIC-CONTROL; FATTY-ACIDS; HDL LEVELS; ESI-MS/MS; PLASMA; EXTRACTION; DISEASE; OBESITY;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36141
Owner only: item control page

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