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Polymorphisms at PRSS1–PRSS2 and CLDN2–MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study

Derikx, M., Hellerbrand, Claus and PanEuropean Working group on Alcoholic Chronic Pancreatitis, members and collaborators (2015) Polymorphisms at PRSS1–PRSS2 and CLDN2–MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut 64, pp. 1426-1433.

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Abstract

Objective: Several genetic risk factors have been identified for non-alcoholic chronic pancreatitis (NACP). A genome-wide association study reported an association of chronic pancreatitis (CP) with variants in PRSS1–PRSS2 (rs10273639; near the gene encoding cationic trypsinogen) and CLDN2–MORC4 loci (rs7057398 in RIPPLY1 and rs12688220 in MORC4). We aimed to refine these findings in a large ...

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Item type:Article
Date:2015
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1136/gutjnl-2014-307453DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36175
Owner only: item control page

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