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Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice

Padrissa-Altés, S., Bachofner, M., Bogorad, R. L., Rossolini, T., Böhm, Friederike, Liebisch, Gerhard and Hellerbrand, Claus (2015) Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice. Gut 64, pp. 1444-1453.

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Date of publication of this fulltext: 12 Sep 2017 12:59

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Abstract

Objective: Fibroblast growth factors (Fgfs) are key orchestrators of development, and a role of Fgfs in tissue repair is emerging. Here we studied the consequences of inducible loss of Fgf receptor (Fgfr) 4, the major Fgf receptor (Fgfr) on hepatocytes, alone or in combination with Fgfr1 and Fgfr2, for liver regeneration after PH. Design: We used siRNA delivered via nanoparticles combined with ...

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Item type:Article
Date:2015
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
10.1136/gutjnl-2014-307874DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36185
Owner only: item control page

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