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Preparation of Propargyl Amines in a ZnCl2–Dimethylurea Deep-Eutectic Solvent

Obst, Martin, Srivastava, Akriti, Baskaran, Sundarababu and König, Burkhard (2018) Preparation of Propargyl Amines in a ZnCl2–Dimethylurea Deep-Eutectic Solvent. Synlett 28, pp. 185-188.

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The coupling of an aldehyde, an amine, and an alkyne to yield propargyl amines was performed in a deep-eutectic solvent composed of zinc chloride and dimethylurea. The deep-eutectic solvent acts simultaneously as catalyst and solvent giving access to a variety of propargyl amines, which were isolated in moderate to very good yields.

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Item type:Article
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:DFG 9209735
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Keywords:deep-eutectic solvent - zinc chloride - dimethylurea - A3-coupling - propargyl amine
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:36272
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