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Freigabe ab: 01.05.2018
New Analogs of Tariquidar: Synthesis, Characterization and Evaluation of their Inhibitory Activity against Breast Cancer Resistance Protein (ABCG2)

Peña Solórzano, Diana Catherine (2018) Freigabe ab: 01.05.2018
New Analogs of Tariquidar: Synthesis, Characterization and Evaluation of their Inhibitory Activity against Breast Cancer Resistance Protein (ABCG2).
PhD, Universität Regensburg.

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Date of publication of this fulltext: 06 Nov 2017 23:04

Abstract (Spanish)

El primer capítulo describe los moduladores específicos de la ABCG2 reportados hasta la fecha, La visión global puede facilitar el diseño racional de nuevos moduladores potentes y seguros. La proteína de resistencia al cáncer de mama (BCRP, ABCG2) es un miembro de la superfamilia de transportadores ATP-binding cassette (ABC) y fue descubierta recientemente. En la fisiología normal actúa como ...

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Translation of the abstract (English)

The first chapter describes the specific modulators of ABCG2 reported to date, The global vision can facilitate the rational design of new powerful and safe modulators. The breast cancer resistance protein (BCRP, ABCG2) is a member of the ATP-binding cassette (ABC) transporter superfamily and was recently discovered. In normal physiology it acts as a detoxification tool in tissue barriers, but in ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:May 2018
Referee:Prof. Dr Oliver Reiser and Prof. Dr Burkhard Koenig and Prof. Dr Rodrigo Abonia and Prof. Dr Claudia Rubiano
Date of exam:11 May 2017
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Keywords:tariquidar, ABCG2, resistance, modulator
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:36305
Owner only: item control page

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