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Bone Morphogenetic Protein-7 Enhances Degradation of Osteoinductive Bioceramic Implants in an Ectopic Model

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Roldán, J. Camilo ; Klünter, Tim ; Schulz, Peter ; Deisinger, Ulrike ; Diez, Claudius ; Waiss, Waltraud ; Kirschneck, Christian ; Reichert, Torsten E. ; Detsch, Rainer
Date of publication of this fulltext: 16 Jan 2018 11:28


Background: The aim of the present study was to evaluate the degradation pattern of highly porous bioceramics as well as the bone formation in presence of bone morphogenetic protein 7 (BMP-7) in an ectopic site. Methods: Novel calcium phosphate ceramic cylinders sintered at 1,300ºC with a total porosity of 92–94 vol%, 45 pores per inch, and sized 15 mm (Ø) × 5 mm were grafted on the musculus ...


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