Bone Morphogenetic Protein-7 Enhances Degradation of Osteoinductive Bioceramic Implants in an Ectopic Model

URN to cite this document:: urn:nbn:de:bvb:355-epub-365279
DOI to cite this document:: 10.5283/epub.36527

Roldán, J. Camilo ; Klünter, Tim ; Schulz, Peter ; Deisinger, Ulrike ; Diez, Claudius ; Waiss, Waltraud ; Kirschneck, Christian ; Reichert, Torsten E. ; Detsch, Rainer

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Date of publication of this fulltext: 16 Jan 2018 11:28

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Abstract

Background: The aim of the present study was to evaluate the degradation pattern of highly porous bioceramics as well as the bone formation in presence of bone morphogenetic protein 7 (BMP-7) in an ectopic site. Methods: Novel calcium phosphate ceramic cylinders sintered at 1,300ºC with a total porosity of 92–94 vol%, 45 pores per inch, and sized 15 mm (Ø) × 5 mm were grafted on the musculus ...