| License: Creative Commons Attribution 4.0 PDF - Submitted Version (2MB) |
- URN to cite this document:
- urn:nbn:de:bvb:355-epub-365386
- DOI to cite this document:
- 10.5283/epub.36538
Abstract
In search for selective ligands for the muscarinic acetylcholine receptor (MR) subtype M-2, the dimeric ligand approach, that is combining two pharmacophores in one and the same molecule, was pursued. Different types (agonists, antagonists, orthosteric, and allosteric) of monomeric MR ligands were combined by various linkers with a dibenzodia-zepinone-type MR antagonist, affording five types of ...

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