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miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment

Mayer, Ute, Benditz, Achim and Grässel, Susanne (2017) miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment. Scientific Reports 7 (13297), pp. 1-14.

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Date of publication of this fulltext: 22 Jan 2018 09:36

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Other URL: http://doi.org/10.1038/s41598-017-13567-x, https://www.nature.com/articles/s41598-017-13567-x

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Osteoarthritis (OA) is characterized by a slowly progressing, irreversible loss of articular cartilage. Tissue engineering approaches for cartilage regeneration include stem cell-based strategies but not much is known about their repair capacity in an OA microenvironment. The aim of the present study was to identify factors regulating collagen expression during chondrogenic differentiation of ...

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Item type:Article
Date:26 October 2017
Institutions:Medicine > Lehrstuhl für Orthopädie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1038/s41598-017-13567-xDOI
Keywords:MESENCHYMAL STEM-CELLS; MICRORNA EXPRESSION; ARTICULAR-CARTILAGE; CHONDROCYTES; BIOGENESIS; APOPTOSIS; GENOMICS; FAMILY;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36542
Owner only: item control page

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