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Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing

Lin, Dasheng, Alberton, Paolo, Caceres, Manuel Delgado, Volkmer, Elias, Schieker, Matthias and Docheva, Denitsa (2017) Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing. Cell Death and Disease 8 (10), e3116.

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Date of publication of this fulltext: 22 Jan 2018 11:16

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Other URL: http://doi.org/10.1038/cddis.2017.510, https://www.nature.com/articles/cddis2017510

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Tenomodulin (Tnmd) is the best-known mature marker for tendon and ligament lineage cells. It is important for tendon maturation, running performance and has key implications for the resident tendon stem/progenitor cells (TSPCs). However, its exact functions during the tendon repair process still remain elusive. Here, we established an Achilles tendon injury model in a Tnmd knockout (Tnmd(-/-)) ...

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Item type:Article
Date:12 October 2017
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1038/cddis.2017.510DOI
Keywords:ROTATOR CUFF REPAIR; STEM/PROGENITOR CELLS; CHONDROMODULIN-I; EXTRACELLULAR-MATRIX; GENE-EXPRESSION; SELF-RENEWAL; PPAR-GAMMA; MOLECULAR-CLONING; ADIPOSE-TISSUE; FIBROSIS;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36546
Owner only: item control page

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