Go to content
UR Home

Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

Kühne, Louisa, Jung, Bettina, Poth, Helen, Schuster, Antonia, Wurm, Simone, Ruemmele, Petra, Banas, Bernhard and Bergler, Tobias (2017) Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy. BMC Immunology 18 (1), pp. 1-14.

[img]
Preview
License: Creative Commons Attribution 4.0
PDF - Published Version
Download (2MB)
Date of publication of this fulltext: 29 Jan 2018 17:52

at publisher (via DOI)

Other URL: http://doi.org/10.1186/s12865-017-0236-6, https://bmcimmunol.biomedcentral.com/articles/10.1186/s12865-017-0236-6

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Background: Non-adherence has been associated with reduced graft survival. The aim of this study was to investigate the immunological mechanisms underlying chronic renal allograft rejection using a model of non-adherence to immunosuppressive therapy. We used a MHC (major histocompatibility complex) -mismatched rat model of renal transplantation (Brown Norway to Lewis), in which rats received ...

plus


Export bibliographical data



Item type:Article
Date:19 December 2017
Institutions:Medicine > Abteilung für Nephrologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s12865-017-0236-6DOI
Keywords:CELL-ACTIVATING FACTOR; KIDNEY-TRANSPLANT FAILURE; MEDIATED REJECTION; AUTOIMMUNE-DISEASE; SJOGRENS-SYNDROME; IMMUNE-RESPONSE; HLA ANTIBODIES; EXPRESSION; BAFF; NEOGENESIS; Donor specific antibodies; Humoral rejection; Renal transplantation; Non-adherence; Leukocyte infiltration; BAFF
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36642
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons