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Haubner, Frank ; Gassner, Holger G. ; Brawanski, Alexander ; Schebesch, Karl-Michael

Fluorescein sodium-guided surgery of parotid gland tumors as a technical advance

Haubner, Frank, Gassner, Holger G., Brawanski, Alexander und Schebesch, Karl-Michael (2017) Fluorescein sodium-guided surgery of parotid gland tumors as a technical advance. BMC Ear, Nose and Throat Disorders 17 (1), S. 1-5.

Veröffentlichungsdatum dieses Volltextes: 30 Jan 2018 08:54
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.36656


Zusammenfassung

Background Complete tumor removal and preservation of the facial nerve are essential in parotid gland surgery. A technical adjunct that potentially enhances the contrast between the facial nerve and the adherent tumor tissue and allows to identify residual tumor tissue could be Fluorescein Sodium. Methods Retrospective chart analysis on 7 patients with benign parotid gland lesions that were ...

Background
Complete tumor removal and preservation of the facial nerve are essential in parotid gland surgery. A technical adjunct that potentially enhances the contrast between the facial nerve and the adherent tumor tissue and allows to identify residual tumor tissue could be Fluorescein Sodium.

Methods
Retrospective chart analysis on 7 patients with benign parotid gland lesions that were operated using Fluorescein Sodium intravenously and the application of the YELLOW 560 nm filter of the operating microscope. Safety and feasibility were evaluated.

Results
All tumors showed fluorescence and the rating ´contrast-enhancing´ was assigned in all cases. In 2 patients, satellite nodules were identified and resected meaning that the fluorescence staining of the tumor margins was significantly better than under white light.

Conclusion
The use of Fluorescein Sodium in parotidectomy is promising. In two cases residual tumor was detected that would have been left behind under white light. Further research in parotid gland surgery and other head and neck tumor procedures is warranted.



Beteiligte Einrichtungen


Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftBMC Ear, Nose and Throat Disorders
Verlag:BMC
Band:17
Nummer des Zeitschriftenheftes oder des Kapitels:1
Seitenbereich:S. 1-5
Datum28 Juni 2017
InstitutionenMedizin > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Identifikationsnummer
WertTyp
10.1186/s12901-017-0039-7DOI
Stichwörter / KeywordsParotid gland, Fluorescein sodium, Parotidectomy
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-366564
Dokumenten-ID36656

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