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Fluorescein sodium-guided surgery of parotid gland tumors as a technical advance
Haubner, Frank, Gassner, Holger G., Brawanski, Alexander and Schebesch, Karl-Michael (2017) Fluorescein sodium-guided surgery of parotid gland tumors as a technical advance. BMC Ear, Nose and Throat Disorders 17 (1), pp. 1-5.Date of publication of this fulltext: 30 Jan 2018 08:54
Article
DOI to cite this document: 10.5283/epub.36656
Abstract
Background Complete tumor removal and preservation of the facial nerve are essential in parotid gland surgery. A technical adjunct that potentially enhances the contrast between the facial nerve and the adherent tumor tissue and allows to identify residual tumor tissue could be Fluorescein Sodium. Methods Retrospective chart analysis on 7 patients with benign parotid gland lesions that were ...
Background
Complete tumor removal and preservation of the facial nerve are essential in parotid gland surgery. A technical adjunct that potentially enhances the contrast between the facial nerve and the adherent tumor tissue and allows to identify residual tumor tissue could be Fluorescein Sodium.
Methods
Retrospective chart analysis on 7 patients with benign parotid gland lesions that were operated using Fluorescein Sodium intravenously and the application of the YELLOW 560 nm filter of the operating microscope. Safety and feasibility were evaluated.
Results
All tumors showed fluorescence and the rating ´contrast-enhancing´ was assigned in all cases. In 2 patients, satellite nodules were identified and resected meaning that the fluorescence staining of the tumor margins was significantly better than under white light.
Conclusion
The use of Fluorescein Sodium in parotidectomy is promising. In two cases residual tumor was detected that would have been left behind under white light. Further research in parotid gland surgery and other head and neck tumor procedures is warranted.
Involved Institutions
Details
| Item type | Article | ||||
| Journal or Publication Title | BMC Ear, Nose and Throat Disorders | ||||
| Publisher: | BMC | ||||
|---|---|---|---|---|---|
| Volume: | 17 | ||||
| Number of Issue or Book Chapter: | 1 | ||||
| Page Range: | pp. 1-5 | ||||
| Date | 28 June 2017 | ||||
| Institutions | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde | ||||
| Identification Number |
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| Keywords | Parotid gland, Fluorescein sodium, Parotidectomy | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-366564 | ||||
| Item ID | 36656 |
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