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Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells

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Schüler-Toprak, Susanne ; Moehle, Christoph ; Skrzypczak, Maciej ; Ortmann, Olaf ; Treeck, Oliver
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 30 Jan 2018 09:11


Background: Estrogen receptor (ER) beta has been suggested to affect ovarian carcinogenesis. We examined the effects of four ER beta agonists on proliferation and gene expression of two ovarian cancer cell lines. Methods: OVCAR-3 and OAW-42 ovarian cancer cells were treated with the ER beta agonists ERB-041, WAY200070, Liquiritigenin and 3 beta-Adiol and cell growth was measured by means of the ...


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