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Immunomodulation by NOD2/CARD15 and Vitamin D3

Saraiva de Matos, Carina (2018) Immunomodulation by NOD2/CARD15 and Vitamin D3. PhD, Universität Regensburg.

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Date of publication of this fulltext: 12 Feb 2018 09:20

Abstract (English)

GvHD is still the most common life-threatening complication associated with allogeneic hematopoietic stem cell transplantation (HSCT). NOD2/CARD15, an intra-cytoplasmatic pathogen-recognition receptor recognizing bacterial muramyl dipeptide (MDP), has gained substantial interest, as single nucleotide polymorphisms (SNPs) of this receptor have been identified as a risk factor for Crohn´s disease ...

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Translation of the abstract (German)

Die GvHD gilt nach wie vor als die häufigste, lebensbedrohliche Komplikation, die bei einer allogenen hämatopoetischen Stammzelltransplantation (HSZT) auftreten kann. NOD2/CARD15, ein pathogen-spezifischer Rezeptor im Zytoplasma, der das bakterielle Muramyl-Dipeptid (MDP) erkennt, hat zunehmend an Bedeutung gewonnen, da Einzelnukleotid-Polymorphismen (SNPs) dieses Rezeptors als Risikofaktor für ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:5 February 2018
Referee:Prof. Dr. Marina Kreutz
Date of exam:29 January 2018
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Keywords:Vitamin D3; NOD2/CARD15; Immunomodulation
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36710
Owner only: item control page

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