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Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice

Rom-Jurek, Eva-Maria , Kirchhammer, Nicole, Ugocsai, Peter, Ortmann, Olaf, Wege, Anja and Brockhoff, Gero (2018) Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice. International Journal of Molecular Sciences 19 (2), p. 563.

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Date of publication of this fulltext: 23 Apr 2018 10:54

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Other URL: http://doi.org/10.3390/ijms19020563, http://www.mdpi.com/1422-0067/19/2/563


Abstract

Programmed death ligand 1 (PD-L1) expression is an efficient strategy of tumor cells to escape immunological eradiation. However, only little is known about the factors that affect the cellular expression levels. Here we assessed the PD-L1 expression on different breast cancer cell lines under standard in vitro culture conditions and as a function of Epirubicin or Paclitaxel treatment. Moreover, ...

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Item type:Article
Date:13 February 2018
Institutions:Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde)
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/ijms19020563DOI
Keywords:breast cancer cell lines; PD-(L)1; humanized tumor mice; Epirubicin; Paclitaxel
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36790
Owner only: item control page

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