Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice

URN to cite this document:: urn:nbn:de:bvb:355-epub-367909
DOI to cite this document:: 10.5283/epub.36790

Rom-Jurek, Eva-Maria

; Kirchhammer, Nicole ; Ugocsai, Peter ; Ortmann, Olaf ; Wege, Anja ; Brockhoff, Gero

Preview

License: Creative Commons Attribution 4.0
PDF
(479kB)

Date of publication of this fulltext: 23 Apr 2018 10:54

Alternative links to fulltext:DOI Publisher Publisher

Details

Preview

Indexed in

Export bibliographical data

Abstract

Programmed death ligand 1 (PD-L1) expression is an efficient strategy of tumor cells to escape immunological eradiation. However, only little is known about the factors that affect the cellular expression levels. Here we assessed the PD-L1 expression on different breast cancer cell lines under standard in vitro culture conditions and as a function of Epirubicin or Paclitaxel treatment. Moreover, ...