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Chromatin Control by the Human Cytomegalovirus Immediate-Early 1 Protein

Pothmann, Daniela (2019) Chromatin Control by the Human Cytomegalovirus Immediate-Early 1 Protein. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Jan 2019 07:51

Abstract (English)

Human cytomegalovirus (hCMV), one of eight human herpesviruses, establishes lifelong "latent" infections in 40-100% of people worldwide. HCMV replication following primary infection or reactivation is known for causing developmental defects in human embryos and life-threatening disease in immunocompromised individuals, but preventive and therapeutic options are still limited. One potential ...


Translation of the abstract (German)

Das humane Cytomegalievirus (hCMV), eines von acht humanen Herpesviren, etabliert lebenslange "latente" Infektionen in 40-100% der Weltbevölkerung. Die hCMV-Replikation nach Primärinfektion oder Reaktivierung ist ursächlich für Entwicklungsdefekte bei menschlichen Embryonen und lebensbedrohlichen Krankheiten in immungeschwächten Personen, jedoch sind die präventiven und therapeutischen ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:11 January 2019
Referee:Prof. Dr. Michael M. Nevels
Date of exam:12 January 2018
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Keywords:HCMV, IE1, CTD, Chromatin, Latency, DNA Damage Response
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36795
Owner only: item control page


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