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Chromatin Control by the Human Cytomegalovirus Immediate-Early 1 Protein

Pothmann, Daniela (2019) Chromatin Control by the Human Cytomegalovirus Immediate-Early 1 Protein. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Jan 2019 07:51

Abstract (English)

Human cytomegalovirus (hCMV), one of eight human herpesviruses, establishes lifelong "latent" infections in 40-100% of people worldwide. HCMV replication following primary infection or reactivation is known for causing developmental defects in human embryos and life-threatening disease in immunocompromised individuals, but preventive and therapeutic options are still limited. One potential ...

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Translation of the abstract (German)

Das humane Cytomegalievirus (hCMV), eines von acht humanen Herpesviren, etabliert lebenslange "latente" Infektionen in 40-100% der Weltbevölkerung. Die hCMV-Replikation nach Primärinfektion oder Reaktivierung ist ursächlich für Entwicklungsdefekte bei menschlichen Embryonen und lebensbedrohlichen Krankheiten in immungeschwächten Personen, jedoch sind die präventiven und therapeutischen ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:11 January 2019
Referee:Prof. Dr. Michael M. Nevels
Date of exam:12 January 2018
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Keywords:HCMV, IE1, CTD, Chromatin, Latency, DNA Damage Response
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36795
Owner only: item control page

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