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Chromatin Control by the Human Cytomegalovirus Immediate-Early 1 Protein

URN to cite this document:
urn:nbn:de:bvb:355-epub-367955
DOI to cite this document:
10.5283/epub.36795
Pothmann, Daniela
Date of publication of this fulltext: 11 Jan 2019 07:51


Abstract (English)

Human cytomegalovirus (hCMV), one of eight human herpesviruses, establishes lifelong "latent" infections in 40-100% of people worldwide. HCMV replication following primary infection or reactivation is known for causing developmental defects in human embryos and life-threatening disease in immunocompromised individuals, but preventive and therapeutic options are still limited. One potential ...

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Translation of the abstract (German)

Das humane Cytomegalievirus (hCMV), eines von acht humanen Herpesviren, etabliert lebenslange "latente" Infektionen in 40-100% der Weltbevölkerung. Die hCMV-Replikation nach Primärinfektion oder Reaktivierung ist ursächlich für Entwicklungsdefekte bei menschlichen Embryonen und lebensbedrohlichen Krankheiten in immungeschwächten Personen, jedoch sind die präventiven und therapeutischen ...

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