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Evidence for cooperative Na+ and Cl- binding by strongly hydrated L-​proline

URN to cite this document:
urn:nbn:de:bvb:355-epub-368243
DOI to cite this document:
10.5283/epub.36824
Dmitrieva, Olga A. ; Fedotova, Marina V. ; Buchner, Richard
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Date of publication of this fulltext: 01 Mar 2018 09:35


Abstract

In Nature, L-proline (Pro) is a ubiquitous and highly effective osmolyte protecting cells against osmotic stress. To understand this effect, knowledge of the hydration of Pro and its interactions with dissolved salts is essential. We studied these properties by combining statistical mechanics and broadband dielec. spectroscopy and found that Pro remains strongly hydrated up to high amino acid ...

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