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Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver

Krautbauer, Sabrina ; Wanninger, Josef ; Eisinger, Kristina ; Hader, Yvonne ; Beck, Michael ; Kopp, Andrea ; Schmid, Andreas ; Weiss, Thomas S. ; Dorn, Christoph ; Buechler, Christa



Abstract

Chemerin is a recently described adipokine whose adipose tissue and serum levels are increased in obesity. Chemerin is expressed in the liver, and here, expression of chemerin has been studied in liver cells and in non-alcoholic fatty liver disease (NAFLD) which is more often found in obesity. Chemerin is shown to be highly expressed in primary human hepatocytes (PHH) whereas hepatic stellate ...

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