Tissue Engineering of Large Full-Size Meniscus Defects by a Polyurethane Scaffold: Accelerated Regeneration by Mesenchymal Stromal Cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-373236
DOI to cite this document:: 10.5283/epub.37323

Koch, Matthias ; Achatz, Felix P. ; Lang, Siegmund ; Pfeifer, Christian G. ; Pattappa, Girish

; Kujat, Richard ; Nerlich, Michael ; Angele, Peter ; Zellner, Johannes

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Date of publication of this fulltext: 15 May 2018 09:20

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Abstract

The endogenous healing potential of avascular meniscal lesions is poor. Up to now, partial meniscectomy is still the treatment of choice for meniscal lesions within the avascular area. However, the large loss of meniscus substance predisposes the knee for osteoarthritic changes. Tissue engineering techniques for the replacement of such lesions could be a promising alternative treatment option. ...