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Regulation of translation and alternative splicing by the Drosophila RNA-binding protein Sister-of-Sex-lethal

URN to cite this document:
urn:nbn:de:bvb:355-epub-374185
Moschall, Rebecca
Date of publication of this fulltext: 07 Jan 2019 06:11


Abstract (English)

In Drosophila melanogaster, the protein Sxl Lethal (Sxl) is the master regulator of female development, controlling sex-specific differences in morphology, behaviour and dosage compensation. The female-specific protein is involved in a variety of posttranscriptional regulatory pathways, which have been intensively studied during the past decades. In contrast, the molecular function of its ...

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Translation of the abstract (German)

Das RNA Bindeprotein Sex Lethal (Sxl) ist der Hauptregulator der weiblichen Fliegenentwicklung in Drosophila melanogaster, indem es die geschlechtsabhängige Morphologie und das Verhalten reguliert und die Dosiskompensation kontrolliert. Das Weibchen-spezifische Protein wirkt in einer Vielzahl von post-transkriptionellen Mechanismen, welche über die letzten Jahrzehnte intensiv untersucht worden ...

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