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Impact of Hydroxyglutarate on Dendritic Cell Activation

Cardenas-Conejo, Zugey Elizabeth (2019) Impact of Hydroxyglutarate on Dendritic Cell Activation. PhD, Universität Regensburg.

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Date of publication of this fulltext: 19 Jun 2019 04:49

Abstract (English)

Tumor development is commonly associated with genetic alterations such as activation of oncogenes or the silencing of tumor suppressor genes. Recently point mutations in genes encoding isocitrate dehydrogenase (IDH) have gained substantial interest in glioma classification. IDH mutations are also frequently found in neoplasias including acute myeloid leukemia (AML). Mutated IDH aquires the ...

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Translation of the abstract (German)

Tumoren werden durch Mutationen in Protoonkogenen und Tumorsurpressorgenen verursacht. Diese Mutationen führen entweder zur Aktivierung von Onkogenen oder zum Stilllegen von Tumorsupressorgenen. Aktuell wurden Punktmutationen im Gen der Isocitrat-Dehydrogenase (IDH) für die Klassifizierung von Gliomen beschrieben. IDH Mutationen werden neben dem Gliom, häufig in der Akuten myeloischen Leukämie ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:19 June 2019
Referee:Prof.Dr Marina Kreutz and Prof.Dr Wolfgang Müller-Klieser and Prof. Dr Wolfram Gronwald and Prof. Dr Richard Warth and Prof. Dr Stephan Schneuwly
Date of exam:18 June 2018
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Keywords:2-Hydroxyglutarate, Dendritic Cells, Metabolism
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37495
Owner only: item control page

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