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Time course of hepatitis E-specific antibodies in adults
Schemmerer, Mathias, Rauh, C., Jilg, Wolfgang und Wenzel, J. J.
(2016)
Time course of hepatitis E-specific antibodies in adults.
Journal of Viral Hepatitis 24 (1), S. 75-79.
Veröffentlichungsdatum dieses Volltextes: 02 Aug 2018 10:01
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.37503
Zusammenfassung
Hepatitis E virus (HEV) is highly endemic in industrialized countries, but there is a lack of knowledge on individual and overall antibody concentration dynamics. The aim of this study was to characterize longitudinal concentration changes of anti-HEV immunoglobulin G (anti-HEV IgG) by enzyme immunoassay (EIA). In total, 199 serum samples collected from 45 subjects over 18years were analysed. A ...
Hepatitis E virus (HEV) is highly endemic in industrialized countries, but there is a lack of knowledge on individual and overall antibody concentration dynamics. The aim of this study was to characterize longitudinal concentration changes of anti-HEV immunoglobulin G (anti-HEV IgG) by enzyme immunoassay (EIA). In total, 199 serum samples collected from 45 subjects over 18years were analysed. A wide range of anti-HEV IgG levels was found. Overall, anti-HEV IgG significantly decreased after an observation period of at least 5years. One negative seroconversion was observed. Four individual profiles suggested single and even multiple HEV reinfections despite pre-existing HEV antibodies.
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| Dokumentenart | Artikel | ||||||
| Titel eines Journals oder einer Zeitschrift | Journal of Viral Hepatitis | ||||||
| Verlag: | Wiley | ||||||
|---|---|---|---|---|---|---|---|
| Ort der Veröffentlichung: | HOBOKEN | ||||||
| Band: | 24 | ||||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 1 | ||||||
| Seitenbereich: | S. 75-79 | ||||||
| Datum | 2016 | ||||||
| Institutionen | Medizin > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin | ||||||
| Identifikationsnummer |
| ||||||
| Stichwörter / Keywords | E VIRUS TRANSMISSION; INFECTION; GERMANY; FRANCE; antibody dynamics; anti-HEV IgG; hepatitis E virus; negative seroconversion; reinfection | ||||||
| Dewey-Dezimal-Klassifikation | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||||
| Status | Veröffentlicht | ||||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||||
| An der Universität Regensburg entstanden | Ja | ||||||
| Dokumenten-ID | 37503 |
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