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Time course of hepatitis E-specific antibodies in adults
Schemmerer, Mathias, Rauh, C., Jilg, Wolfgang and Wenzel, J. J.
(2016)
Time course of hepatitis E-specific antibodies in adults.
Journal of Viral Hepatitis 24 (1), pp. 75-79.
Date of publication of this fulltext: 02 Aug 2018 10:01
Article
DOI to cite this document: 10.5283/epub.37503
Abstract
Hepatitis E virus (HEV) is highly endemic in industrialized countries, but there is a lack of knowledge on individual and overall antibody concentration dynamics. The aim of this study was to characterize longitudinal concentration changes of anti-HEV immunoglobulin G (anti-HEV IgG) by enzyme immunoassay (EIA). In total, 199 serum samples collected from 45 subjects over 18years were analysed. A ...
Hepatitis E virus (HEV) is highly endemic in industrialized countries, but there is a lack of knowledge on individual and overall antibody concentration dynamics. The aim of this study was to characterize longitudinal concentration changes of anti-HEV immunoglobulin G (anti-HEV IgG) by enzyme immunoassay (EIA). In total, 199 serum samples collected from 45 subjects over 18years were analysed. A wide range of anti-HEV IgG levels was found. Overall, anti-HEV IgG significantly decreased after an observation period of at least 5years. One negative seroconversion was observed. Four individual profiles suggested single and even multiple HEV reinfections despite pre-existing HEV antibodies.
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Details
| Item type | Article | ||||||
| Journal or Publication Title | Journal of Viral Hepatitis | ||||||
| Publisher: | Wiley | ||||||
|---|---|---|---|---|---|---|---|
| Place of Publication: | HOBOKEN | ||||||
| Volume: | 24 | ||||||
| Number of Issue or Book Chapter: | 1 | ||||||
| Page Range: | pp. 75-79 | ||||||
| Date | 2016 | ||||||
| Institutions | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin | ||||||
| Identification Number |
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| Keywords | E VIRUS TRANSMISSION; INFECTION; GERMANY; FRANCE; antibody dynamics; anti-HEV IgG; hepatitis E virus; negative seroconversion; reinfection | ||||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||||
| Status | Published | ||||||
| Refereed | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg | Yes | ||||||
| Item ID | 37503 |
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