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Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators

Pen͂a-Solȯrzano, Diana, Scholler, Matthias, Bernhardt, Günther , Buschauer, Armin , König, Burkhard and Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS Medicinal Chemistry Letters 9, pp. 854-859.

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Abstract

ABC transporters, including ABCG2, play a vital role in defending the human body against the vast range of xenobiotics. Even though this is beneficial for human health, these protein transporters have been implicated in the emerging resistance of cancer cells to a variety of structurally and functionally diverse anticancer drugs. In order to investigate their role in resistance, potent and ...

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Item type:Article
Date:2018
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Identification Number:
ValueType
10.1021/acsmedchemlett.8b00289DOI
30128080PubMed ID
Keywords:Tariquidar; chalcone; ketone; ABCG2; modulator
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:37578
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