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Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators

Peña-Solórzano, Diana ; Scholler, Matthias ; Bernhardt, Günther ; Buschauer, Armin ; König, Burkhard ; Ochoa-Puentes, Cristian


ABC transporters, including ABCG2, play a vital role in defending the human body against the vast range of xenobiotics. Even though this is beneficial for human health, these protein transporters have been implicated in the emerging resistance of cancer cells to a variety of structurally and functionally diverse anticancer drugs. In order to investigate their role in resistance, potent and ...


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