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Galectin-3 Modulates Experimental Colitis

Lippert, Elisabeth, Stieber-Gunckel, Manuela, Dunger, Nadja, Falk, Werner, Obermeier, Florian and Kunst, Claudia (2015) Galectin-3 Modulates Experimental Colitis. Digestion 92 (1), pp. 45-53.

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Background: We recently identified galectin-3 (gal-3) as a new and strong fibroblast activator produced by colonic epithelial cells. Very little is known about the influence of gal-3 in inflammatory bowel disease. We, therefore, investigated the impact of gal-3 on dextran sodium sulfate (DSS)-induced colitis in a mouse model. Methods: Colonic lamina propria fibroblasts of healthy controls were ...


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Item type:Article
Date:17 July 2015
Institutions:Medicine > Lehrstuhl für Innere Medizin I
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Keywords:Colitis, Crohn's disease, Inflammation, Inflammatory bowel disease, Ulcerative colitis, Galectin-3
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37657
Owner only: item control page


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