Comparative Analysis of Gender-Related Differences in Symptoms and Referral Patterns prior to Initial Diagnosis of Urothelial Carcinoma of the Bladder: A Prospective Cohort Study

URN to cite this document:

urn:nbn:de:bvb:355-epub-376604 Copy

DOI to cite this document:

10.5283/epub.37660 Copy

Aziz, Atiqullah ; Madersbacher, Stephan ; Ott, Wolfgang ; Mayr, Roman ; Comploj, Evi ; Pycha, Armin ; Denzinger, Stefan ; Fritsche, Hans-Martin

License: Allianz- bzw. Nationallizenz PDF - Published Version (741kB)

Date of publication of this fulltext: 28 Aug 2018 13:25

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Details

Item type:	Article
Open Access Type:	Alliance-/National licence
Journal or Publication Title:	Urologia Internationalis
Publisher:	Karger
Volume:	94
Number of Issue or Book Chapter:	1
Page Range:	pp. 37-44
Date:	2015
Institutions:	Medicine > Lehrstuhl für Urologie
Identification Number:	Value Type 10.1159/000363334 DOI
Keywords:	Urinary bladder neoplasms Carcinoma, Transitional cell, Sex characteristics, Referrals
Dewey Decimal Classification:	600 Technology > 610 Medical sciences Medicine
Status:	Published
Refereed:	Yes, this version has been refereed
Created at the University of Regensburg:	Yes
Item ID:	37660

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Abstract

Objective: To analyze gender-specific differences regarding clinical symptoms, referral patterns and tumor biology prior to initial diagnosis of urothelial carcinoma of the bladder (UCB). Methods: A consecutive series of patients with an initial diagnosis of UCB was included. All patients completed a questionnaire on demographics, clinical symptoms and referral patterns. Results: In total, 68 ...

Abstract

Objective: To analyze gender-specific differences regarding clinical symptoms, referral patterns and tumor biology prior to initial diagnosis of urothelial carcinoma of the bladder (UCB). Methods: A consecutive series of patients with an initial diagnosis of UCB was included. All patients completed a questionnaire on demographics, clinical symptoms and referral patterns. Results: In total, 68 patients (50 men, 18 women) with newly diagnosed UCB at admission for transurethral resection of bladder tumors were recruited. Dysuria was more often observed in women (55.6 vs. 38.0%, p = 0.001). Direct consultation of the urologist was conducted by 84.0% of males and 66.7% of females (p = 0.120). One third of the women saw their general practitioner and/or gynecologist once or twice (p = 0.120) before referral to the urologist. Furthermore, women were significantly more often treated for urinary tract infections than men (61.1 vs. 20.0%, p = 0.005). Cystoscopy at first presentation to the urologist was more often performed in men than women (88.0 vs. 66.7%, p = 0.068), with a more favorable tumor detection rate at first cystoscopy in men (96.0 vs. 50.0%, p < 0.001). Conclusions: Delayed referral patterns might lead to deferred diagnosis of UCB and consequently to adverse outcome. Thus, primary care physicians might consider referring patients with bladder complaints to specialized care earlier.

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