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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-376621
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.37662
Zusammenfassung
The tissue availability of active glucocorticoids (cortisol in humans) depends on their rate of synthesis from cholesterol, downstream metabolism, excretion and interconversion. The latter is mediated by the 11β-hydroxysteroid dehydrogenases (11βHSDs). In this review, we summarize the features of the two isoenzymes, 11βHSD1 and 11βHSD2, and current available experimental data related to 11βHSDs, ...
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