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In Vitro Comparison of 2D-Cell Culture and 3D-Cell Sheets of Scleraxis-Programmed Bone Marrow Derived Mesenchymal Stem Cells to Primary Tendon Stem/Progenitor Cells for Tendon Repair

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Docheva, Denitsa ; Hsieh, Chi-Fen ; Schumann, Ricarda ; Yan, Zexing ; Milz, Stefan ; Pfeifer, Christian ; Schieker, Matthias
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Date of publication of this fulltext: 30 Aug 2018 07:21


The poor and slow healing capacity of tendons requires novel strategies to speed up the tendon repair process. Hence, new and promising developments in tendon tissue engineering have become increasingly relevant. Previously, we have established a tendon progenitor cell line via ectopic expression of the tendon-related basic helix-loop-helix (bHLH) transcription factor Scleraxis (Scx) in human ...


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