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Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis

Wirth, Anna M., Khomenko, Andrei, Baldaranov, Dobri, Kobor, Ines, Hsam, Ohnmar, Grimm, Thomas, Johannesen, Siw, Bruun, Tim-Henrik, Schulte-Mattler, Wilhelm, Greenlee, Mark W. and Bogdahn, Ulrich (2018) Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis. Frontiers in Neurology 9 (614).

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Date of publication of this fulltext: 30 Aug 2018 13:07

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Other URL: http://doi.org/10.3389/fneur.2018.00614, https://www.frontiersin.org/articles/10.3389/fneur.2018.00614/full


Abstract

Objective: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative process affecting upper and lower motor neurons as well as non-motor systems. In this study, precentral and postcentral cortical thinning detected by structural magnetic resonance imaging (MRI) were combined with clinical (ALS-specific functional rating scale revised, ALSFRS-R) and neurophysiological (motor unit ...

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Item type:Article
Date:30 July 2018
Institutions:Medicine > Lehrstuhl für Neurologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3389/fneur.2018.00614DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37677
Owner only: item control page

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