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"Bligh and Dyer" and folch methods for solid-​liquid-​liquid extraction of lipids from microorganisms. Comprehension of solvatation mechanisms and towards substitution with alternative solvents

Breil, Cassandra, Vian, Maryline Abert, Zemb, Thomas, Kunz, Werner and Chemat, Farid (2017) "Bligh and Dyer" and folch methods for solid-​liquid-​liquid extraction of lipids from microorganisms. Comprehension of solvatation mechanisms and towards substitution with alternative solvents. International Journal of Molecular Sciences 18 (4), pp. 708-728.

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Abstract

Bligh and Dyer (B & D) or Folch procedures for the extraction and separation of lipids from microorganisms and biological tissues using chloroform/methanol/water have been used tens of thousands of times and are "gold standards" for the analysis of extracted lipids. Based on the Conductor-like Screening MOdel for realistic Solvatation (COSMO-RS), we select ethanol and ethyl acetate as being ...

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Item type:Article
Date:2017
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz
Identification Number:
ValueType
10.3390/ijms18040708DOI
Keywords:BIO-BASED SOLVENTS; CELL-WALL; SACCHAROMYCES-CEREVISIAE; RAPID METHOD; COSMO-RS; CELLULOSIC BIOETHANOL; YEAST; MICROWAVE; PURIFICATION; ULTRASOUND; Bligh and Dyer; Folch; bio-sourced solvent; yeast; lipids
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37723
Owner only: item control page

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