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Postoperative cellular stress in the kidney is associated with an early systemic γδ T-cell immune cell response

URN to cite this document:
urn:nbn:de:bvb:355-epub-377991
DOI to cite this document:
10.5283/epub.37799
Göcze, Ivan ; Ehehalt, Katharina ; Zeman, Florian ; Riquelme, Paloma ; Pfister, Karin ; Graf, Bernhard M. ; Bein, Thomas ; Geissler, Edward K. ; Kasprzak, Piotr ; Schlitt, Hans J. ; Kellum, John A. ; Hutchinson, James A. ; Eggenhofer, Elke ; Renner, Philipp
Date of publication of this fulltext: 28 Sep 2018 06:29



Abstract

Background: Basic science data suggest that acute kidney injury (AKI) induced by ischemia-reperfusion injury (IRI) is an inflammatory process involving the adaptive immune response. Little is known about the T-cell contribution in the very early phase, so we investigated if tubular cellular stress expressed by elevated cell cycle biomarkers is associated with early changes in circulating T-cell ...

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