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Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration

URN to cite this document:
urn:nbn:de:bvb:355-epub-380733
DOI to cite this document:
10.5283/epub.38073
Pujol-Lereis, Luciana M. ; Liebisch, Gerhard ; Schick, Tina ; Lin, Yuchen ; Grassmann, Felix ; Uchida, Koji ; Zipfel, Peter F. ; Fauser, Sascha ; Skerka, Christine ; Weber, Bernhard H. F.
Date of publication of this fulltext: 22 Nov 2018 14:14



Abstract

Sphingolipids are bioactive molecules associated with oxidative stress, inflammation, and neurodegenerative diseases, but poorly studied in the context of age-related macular degeneration (AMD), a prevalent sight-threatening disease of the ageing retina. Here, we found higher serum levels of hexosylceramide (HexCer) d18:1/16:0 in patients with choroidal neovascularization (CNV) and geographic ...

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