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Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration

Pujol-Lereis, Luciana M., Liebisch, Gerhard, Schick, Tina, Lin, Yuchen, Grassmann, Felix, Uchida, Koji, Zipfel, Peter F., Fauser, Sascha, Skerka, Christine and Weber, Bernhard H. F. (2018) Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration. PLOS ONE 13 (8), e0200739.

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Date of publication of this fulltext: 22 Nov 2018 14:14

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Other URL: http://doi.org/10.1371/journal.pone.0200739, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200739


Abstract

Sphingolipids are bioactive molecules associated with oxidative stress, inflammation, and neurodegenerative diseases, but poorly studied in the context of age-related macular degeneration (AMD), a prevalent sight-threatening disease of the ageing retina. Here, we found higher serum levels of hexosylceramide (HexCer) d18:1/16:0 in patients with choroidal neovascularization (CNV) and geographic ...

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Item type:Article
Date:2 August 2018
Institutions:Medicine > Lehrstuhl für Humangenetik
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0200739DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38073
Owner only: item control page

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