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In Vivo Effects of Neostigmine and Physostigmine on Neutrophil Functions and Evaluation of Acetylcholinesterase and Butyrylcholinesterase as Inflammatory Markers during Experimental Sepsis in Rats

Bitzinger, Diane I. , Gruber, Michael , Tümmler, Simon, Malsy, Manuela , Seyfried, Timo, Weber, Florian, Redel, Andreas, Graf, Bernhard M. and Zausig, York A. (2019) In Vivo Effects of Neostigmine and Physostigmine on Neutrophil Functions and Evaluation of Acetylcholinesterase and Butyrylcholinesterase as Inflammatory Markers during Experimental Sepsis in Rats. Mediators of Inflammation 2019, pp. 1-12.

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Date of publication of this fulltext: 24 Jan 2019 09:54

at publisher (via DOI)

Other URL: http://doi.org/10.1155/2019/8274903, https://www.hindawi.com/journals/mi/2019/8274903/


Abstract

Introduction. Recent studies have shown that acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) may serve as important diagnostic and therapeutic targets in sepsis. Since polymorphonuclear neutrophils (PMNs) play a pivotal role in the early phase of sepsis, we evaluated the potential therapeutic effects of cholinesterase inhibitors on PMN functions during cecal ligation and puncture- ...

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Item type:Article
Date:20 January 2019
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1155/2019/8274903DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38259
Owner only: item control page

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