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Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis

Heudobler, Daniel, Rechenmacher, Michael, Lüke, Florian, Vogelhuber, Martin, Klobuch, Sebastian, Thomas, Simone, Pukrop, Tobias, Hackl, Christina, Herr, Wolfgang, Ghibelli, Lina, Gerner, Christopher and Reichle, Albrecht (2018) Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis. Frontiers in Pharmacology 9 (1357), pp. 1-26.

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Date of publication of this fulltext: 29 Jan 2019 12:44

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Other URL: http://doi.org/10.3389/fphar.2018.01357, https://www.frontiersin.org/articles/10.3389/fphar.2018.01357/full


Classic tumor therapy, consisting of cytotoxic agents and/or targeted therapy, has not overcome therapeutic limitations like poor risk genetic parameters, genetic heterogeneity at different metastatic sites or the problem of undruggable targets. Here we summarize data and trials principally following a completely different treatment concept tackling systems biologic processes: the principle of ...


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Item type:Article
Date:28 November 2018
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Projects:Open Access Publizieren (DFG)
Identification Number:
Keywords:Anakoinosis, communicative reprogramming, transcriptional modulators, metronomic low-dose chemotherapy, glitazones, all-trans retinoic acid, COX-2 inhibitor, master modulators
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38279
Owner only: item control page


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