Use of statins or NSAIDs and survival of patients with high-grade glioma

URN to cite this document:: urn:nbn:de:bvb:355-epub-383111
DOI to cite this document:: 10.5283/epub.38311

Seliger, Corinna ; Schaertl, Julia ; Gerken, Michael ; Luber, Christian ; Proescholdt, Martin ; Riemenschneider, Markus J. ; Leitzmann, Michael F. ; Hau, Peter

; Klinkhammer-Schalke, Monika

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Date of publication of this fulltext: 07 Feb 2019 08:11

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Abstract

Background High-grade glioma (HGG) is associated with a limited prognosis. Drug repurposing has become of increasing interest to improve standard therapy. Statins and NSAIDs inhibit glioma cell growth in vitro and in vivo, but data on statin and NSAID treatment in relation to survival of patients with HGG are sparse. Methods We performed multivariable adjusted Cox-regression analyses among 1,093 ...