Go to content
UR Home

Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA

URN to cite this document:
DOI to cite this document:
Boscheinen, Jan B. ; Thomann, Sabrina ; Knipe, David M. ; DeLuca, Neal ; Schuler-Thurner, Beatrice ; Gross, Stefanie ; Dörrie, Jan ; Schaft, Niels ; Bach, Christian ; Rohrhofer, Anette ; Werner-Klein, Melanie ; Schmidt, Barbara ; Schuster, Philipp
Date of publication of this fulltext: 14 Feb 2019 18:00


Robust anti-tumor immunity requires innate as well as adaptive immune responses. We have shown that plasmacytoid dendritic cells develop killer cell-like activity in melanoma cell cocultures after exposure to the infectious but replication-deficient herpes simplex virus 1 (HSV-1) d 106S. To combine this innate effect with an enhanced adaptive immune response, the gene encoding human MelanA/MART-1 ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons