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Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion

Alieva, Maria, Leidgens, Verena, Riemenschneider, Markus J., Klein, Christoph A. , Hau, Peter and van Rheenen, Jacco (2019) Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion. Scientific Reports 9 (2054), pp. 1-11.

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Date of publication of this fulltext: 18 Feb 2019 07:25

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Other URL: http://doi.org/10.1038/s41598-019-38625-4, https://www.nature.com/articles/s41598-019-38625-4

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

The pathogenesis of glioblastoma (GBM) is characterized by highly invasive behavior allowing dissemination and progression. A conclusive image of the invasive process is not available. The aim of this work was to study invasion dynamics in GBM using an innovative in vivo imaging approach. Primary brain tumor initiating cell lines from IDH-wild type GBM stably expressing H2B-Dendra2 were implanted ...

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Item type:Article
Date:14 February 2019
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1038/s41598-019-38625-4DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38362
Owner only: item control page

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