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The Drosophila fussel gene is required for bitter gustatory neuron differentiation acting within an Rpd3 dependent chromatin modifying complex

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Rass, Mathias ; Oestreich, Svenja ; Guetter, Severin ; Fischer, Susanne ; Schneuwly, Stephan
Date of publication of this fulltext: 01 Mar 2019 07:27


Members of the Ski/Sno protein family are classified as proto-oncogenes and act as negative regulators of the TGF-ss/BMP-pathways in vertebrates and invertebrates. A newly identified member of this protein family is fussel (fuss), the Drosophila homologue of the human functional Smad suppressing elements (fussel-15 and fussel-18). We and others have shown that Fuss interacts with SMAD4 and that ...


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