Kovalska, Vladislava 
, Chernii, Svitlana, Losytskyy, Mykhaylo, Dovbii, Yan, Tretyakova, Iryna, Czerwieniec, Rafal , Gorskii, Aleksandr, Chernii, Viktor and Yarmoluk, Sergiy
(2018)
Design of functionalized b-ketoenole derivatives as efficient fluorescent dyes for detection of amyloid fibrils.
New Journal of Chemistry 42, pp. 13308-13318.
| License: Creative Commons Attribution Non-commercial 3.0 PDF - Published Version Download (2MB) |
Other URL: https://pubs.rsc.org/en/Content/ArticleLanding/2018/NJ/C8NJ01020J#!divAbstract
Abstract
The self-association of proteins into insoluble filamentous aggregates – amyloid fibrils – is associated with a range of protein deposition disorders. With the aim of developing fluorescent probes sensitive to amyloid aggregates, a new series of derivatives of (2Z,5Z,7E)-6-hydroxy-2-(alkylamino)-8-arylocta-2,5,7-trien-4-one dyes was synthesized. These dyes are less sensitive to native ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 12 July 2018 | ||||
| Institutions: | Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry III - Physical Chemistry (Molecular Spectroscopy and Photochemistry) > Prof. Dr. Bernhard Dick | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Partially | ||||
| Item ID: | 38399 |
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