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The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer

Malsy, Manuela, Graf, Bernhard and Almstedt, Katrin (2019) The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer. BMC Biochemistry 20 (1), pp. 1-11.

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Date of publication of this fulltext: 01 Mar 2019 11:29

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Other URL: http://doi.org/10.1186/s12858-019-0105-4, https://bmcbiochem.biomedcentral.com/articles/10.1186/s12858-019-0105-4


Abstract

Background Adenocarcinoma of the pancreas is one of the most aggressive tumor diseases affecting the human body. The oncogenic potential of pancreatic cancer is mainly characterized by extremely rapid growth triggered by the activation of oncogenic signaling cascades, which suggests a change in the regulation of important transcription factors. Amongst others, NFAT transcription factors are ...

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Item type:Article
Date:29 January 2019
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s12858-019-0105-4DOI
Keywords:Sp1; NFATc2; Pancreatic cancer; Binding partner; Cancer; C-terminus; N-terminus; Proliferation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38400
Owner only: item control page

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