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Intravenous hydrogen sulfide does not induce neuroprotection after aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury in a human-like porcine model of ubiquitous arteriosclerosis

Bredthauer, Andre, Lehle, Karla, Scheuerle, Angelika, Schelzig, Hubert, McCook, Oscar, Radermacher, Peter, Szabo, Csaba, Wepler, Martin and Simon, Florian (2018) Intravenous hydrogen sulfide does not induce neuroprotection after aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury in a human-like porcine model of ubiquitous arteriosclerosis. Intensive Care Medicine Experimental 6 (1), pp. 1-14.

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Date of publication of this fulltext: 01 Mar 2019 12:18

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Other URL: http://doi.org/10.1186/s40635-018-0209-y, https://icm-experimental.springeropen.com/articles/10.1186/s40635-018-0209-y


Abstract

Objective In rodents, intravenous sulfide protected against spinal cord ischemia/reperfusion (I/R) injury during aortic balloon occlusion. We investigated the effect of intravenous sulfide on aortic occlusion-induced porcine spinal cord I/R injury. Methods Anesthetized and mechanically ventilated “familial hypercholesterolemia Bretoncelles Meishan” (FBM) pigs with high-fat-diet-induced ...

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Item type:Article
Date:24 October 2018
Institutions:Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s40635-018-0209-yDOI
Keywords:Hydrogen sulfide; I/R injury; Ubiquitous arteriosclerosis; Aortic aneurysm; Neuro protection
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38407
Owner only: item control page

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