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Intravenous hydrogen sulfide does not induce neuroprotection after aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury in a human-like porcine model of ubiquitous arteriosclerosis

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Bredthauer, Andre ; Lehle, Karla ; Scheuerle, Angelika ; Schelzig, Hubert ; McCook, Oscar ; Radermacher, Peter ; Szabo, Csaba ; Wepler, Martin ; Simon, Florian
Date of publication of this fulltext: 01 Mar 2019 12:18


Objective In rodents, intravenous sulfide protected against spinal cord ischemia/reperfusion (I/R) injury during aortic balloon occlusion. We investigated the effect of intravenous sulfide on aortic occlusion-induced porcine spinal cord I/R injury. Methods Anesthetized and mechanically ventilated “familial hypercholesterolemia Bretoncelles Meishan” (FBM) pigs with high-fat-diet-induced ...


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