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The Proline 7 Substitution in the Preproneuropeptide Y Is Associated with Higher Hepatic Lipase Activity In Vivo

Schiekofer, Stephan, Kleber, Marcus E., Maerz, Winfried, Rasche, Franz M. and Schneider, Jochen G. (2017) The Proline 7 Substitution in the Preproneuropeptide Y Is Associated with Higher Hepatic Lipase Activity In Vivo. International Journal of Endocrinology 2017, pp. 1-7.

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Other URL: http://doi.org/10.1155/2017/2869090

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Hepatic lipase (HL) functions as a lipolytic enzyme that hydrolyzes triglycerides and phospholipids present in circulating plasma lipoproteins. Plasma HL activity is known to be regulated by hormonal and metabolic factors, but HL responsiveness to insulin as well as its role in modulating atherosclerotic risk is still controversial. We investigated on the influence of a known polymorphism in the ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
10.1155/2017/2869090DOI
Keywords:CORONARY-ARTERY-DISEASE; NEUROPEPTIDE-Y; SIGNAL PEPTIDE; LEU7PRO POLYMORPHISM; INSULIN-RESISTANCE; CAROTID ATHEROSCLEROSIS; METABOLIC SYNDROME; PRO7 SUBSTITUTION; RAT HEPATOCYTES; HEART-DISEASE;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38461
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