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Circulating serum CK level vs. muscle impairment for in situ monitoring burden of disease in Mdx-mice

Klein, S.M., Prantl, L., Geis, S., Felthaus, O., Dolderer, J., Anker, A.M., Zeitler, K., Alt, E. and Vykoukal, J. (2017) Circulating serum CK level vs. muscle impairment for in situ monitoring burden of disease in Mdx-mice. Clinical Hemorheology and Microcirculation 65 (4), pp. 327-334.

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Other URL: http://doi.org/10.3233/CH-16195


Abstract

BACKGROUND: Duchenne muscular dystrophy (DMD) consists of a lack in the expression of the subsarcolemmal protein dystrophin causing progressive muscle dysfunction. Among the widely applied animal models in DMD research is the C57BL/1010ScSn-Dmdmdx mouse, commonly referred to as the "mdx mouse". The potential benefit of novel interventions in this model is often assessed by variables such as ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
10.3233/CH-16195DOI
Keywords:DUCHENNE MUSCULAR-DYSTROPHY; MOUSE MODEL; SKELETAL; PATHOLOGY; UTROPHIN; CARRIERS; Duchenne muscular dystrophy; mdx mouse; muscle impairment; CK level; diagnostic methods; serum biomarker for muscle imparment
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38468
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