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Effect of melanoma cells on proliferation and migration of activated hepatic stellate cells in vitro

Meyer, Theresa, Koch, Andreas, Ebert, Eva-Vanessa, Czech, Barbara, Mueller, Martina, Bosserhoff, Anja , Lang, Sven Arke and Hellerbrand, Claus (2017) Effect of melanoma cells on proliferation and migration of activated hepatic stellate cells in vitro. Pathology - Research and Practice 213 (4), pp. 400-404.

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Other URL: http://doi.org/10.1016/j.prp.2016.12.014


Abstract

Melanoma is a highly aggressive tumor of the skin. The clinical outcome is determined by the presence or absence of metastases, and the liver is a common site of distant metastases. Hepatic metastasis is causing activation of hepatic stellate cells (HSC), which form the stroma of hepatic metastases and are increasingly recognized as a crucial component of the pro- metastatic liver ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1016/j.prp.2016.12.014DOI
Keywords:HEPATOCELLULAR-CARCINOMA; METASTATIC MELANOMA; LIVER; CANCER; MICROENVIRONMENT; EXPRESSION; CRIME; TOOLS; LINES; Melanoma; Metastasis; Hepatic stellate cells; Migration; Proliferation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38475
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