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PCR analysis is superior to histology for diagnosis of Whipple’s disease mimicking seronegative rheumatic diseases

Lehmann, P, Ehrenstein, B, Hartung, W, Dragonas, C, Reischl, U and Fleck, M (2017) PCR analysis is superior to histology for diagnosis of Whipple’s disease mimicking seronegative rheumatic diseases. Scandinavian Journal of Rheumatology 46 (2), pp. 138-142.

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Other URL: http://doi.org/10.1080/03009742.2016.1183038


Abstract

Objectives: The diagnosis of Whipple's disease (WD) is commonly confirmed by histology demonstrating Periodic Acid Schiff (PAS)-positive macrophages in the duodenal mucosa. Analysis of intestinal tissue or other specimens using polymerase chain reaction (PCR) is a more sensitive method. However, the relevance of positive PCR findings is still controversial. Therefore, we evaluated the relevance ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
10.1080/03009742.2016.1183038DOI
Keywords:TROPHERYMA-WHIPPLEI; HEALTHY PEOPLE; WHIPPELII; SALIVA;
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38486
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