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In vivo performance of an acellular disc-like angle ply structure (DAPS) for total disc replacement in a small animal model

Martin, John T., Kim, Dong Hwa, Milby, Andrew H., Pfeifer, Christian G., Smith, Lachlan J., Elliott, Dawn M., Smith, Harvey E. and Mauck, Robert L. (2016) In vivo performance of an acellular disc-like angle ply structure (DAPS) for total disc replacement in a small animal model. Journal of Orthopaedic Research 35 (1), pp. 23-31.

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Other URL: http://doi.org/10.1002/jor.23310


Abstract

Total intervertebral disc replacement with a biologic engineered disc may be an alternative to spinal fusion for treating end-stage disc disease. In previous work, we developed disc-like angle ply structures (DAPS) that replicate the structure and function of the native disc and a rat tail model to evaluate DAPS in vivo. Here, we evaluated a strategy in which, after in vivo implantation, ...

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Item type:Article
Date:2016
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Identification Number:
ValueType
10.1002/jor.23310DOI
Keywords:INTERVERTEBRAL DISC; LUMBAR DISC; ANNULUS FIBROSUS; CELL PHENOTYPE; MOUSE MODEL; DEGENERATION; COMPLICATIONS; MECHANICS; SCAFFOLDS; TRANSPORT; intervertebral disc; tissue engineering; acellular biomaterials; total disc replacement
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38506
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