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Independent Evolution of Acetolactate Synthase–inhibiting Herbicide Resistance in Weedy Sorghum Populations across Common Geographic Regions

Werle, Rodrigo ; Begcy, Kevin ; Yerka, Melinda K. ; Mower, Jeffrey P. ; Dweikat, Ismail ; Jhala, Amit J. ; Lindquist, John L.


Traditional breeding has been used to develop grain sorghum germplasm that is tolerant to acetolactate synthase (ALS)-inhibiting herbicides (Inzen Technology, DuPont). Inzen sorghum carries a double mutation in the ALS gene (Val(560)Ile and Trp(574)Leu), which confers high level of tolerance to ALS-inhibiting herbicides. Overreliance on ALS-inhibiting herbicides for weed control during the 1990s ...


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