Go to content
UR Home

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo

Asare, Yaw, Ommer, Miriam, Azombo, Florence. A., Alampour-Rajabi, Setareh, Sternkopf, Marieke, Sanati, Maryam, Gijbels, Marion J., Schmitz, Corinna, Sinitski, Dzmitry, Tilstam, Pathricia V., Lue, Hongqi, Gessner, André, Lange, Denise, Schmid, Johannes A., Weber, Christian, Dichgans, Martin, Jankowski, Joachim, Pardi, Ruggero, de Winther, Menno P. J. , Noels, Heidi and Bernhagen, Jürgen (2017) Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proceedings of the National Academy of Sciences 114 (13), E2766-E2775.

Full text not available from this repository.

at publisher (via DOI)

Other URL: http://doi.org/10.1073/pnas.1618411114


Abstract

Constitutive photomorphogenesis 9 (COP9) signalosome 5 (CSN5), an isopeptidase that removes neural precursor cell-expressed, developmentally down-regulated 8 (NEDD8) moieties from cullins (thus termed "deNEDDylase") and a subunit of the cullin-RING E3 ligase-regulating COP9 signalosome complex, attenuates proinflammatory NF-kappa B signaling. We previously showed that CSN5 is up-regulated in ...

plus


Export bibliographical data



Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
10.1073/pnas.1618411114DOI
Keywords:NF-KAPPA-B; NEDD8-ACTIVATING ENZYME-INHIBITOR; E-DEFICIENT MICE; ACUTE MYELOID-LEUKEMIA; MODULATE AP-1 ACTIVITY; EXPERIMENTAL ATHEROSCLEROSIS; ATTENUATES ATHEROSCLEROSIS; ENDOTHELIAL DYSFUNCTION; GENE-EXPRESSION; JAB1 INTERACTS; COP9 signalosome; atherosclerosis; inflammation; NEDDylation; MLN4924
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38587
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons