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Analysis of hepatic transcript profile and plasma lipid profile in early lactating dairy cows fed grape seed and grape marc meal extract

Gessner, Denise K., Winkler, Anne, Koch, Christian, Dusel, Georg, Liebisch, Gerhard , Ringseis, Robert and Eder, Klaus (2017) Analysis of hepatic transcript profile and plasma lipid profile in early lactating dairy cows fed grape seed and grape marc meal extract. BMC Genomics 18 (1).

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Other URL: http://doi.org/10.1186/s12864-017-3638-1

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Background: It was recently reported that dairy cows fed a polyphenol-rich grape seed and grape marc meal extract (GSGME) during the transition period had an increased milk yield, but the underlying reasons remained unclear. As polyphenols exert a broad spectrum of metabolic effects, we hypothesized that feeding of GSGME influences metabolic pathways in the liver which could account for the ...

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Item type:Article
Date:2017
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
10.1186/s12864-017-3638-1DOI
Keywords:ENDOPLASMIC-RETICULUM STRESS; TANDEM MASS-SPECTROMETRY; HIGH-THROUGHPUT QUANTIFICATION; UNFOLDED PROTEIN RESPONSE; FACTOR-KAPPA-B; GENE-EXPRESSION; TRANSITION PERIOD; P53-DEPENDENT APOPTOSIS; INFLAMMATORY CONDITIONS; DIETARY POLYPHENOLS; Transcriptomics; Lipidomics; Dairy cow; Early lactation; Liver; Polyphenols; Grape seed and grape marc meal extract; Endoplasmic reticulum stress; Inflammation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38592
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