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Relief from detrimental consequences of chronic psychosocial stress in mice deficient for the metabotropic glutamate receptor subtype 7

Peterlik, Daniel ; Stangl, Christina ; Bludau, Anna ; Grabski, Dominik ; Strasser, Robert ; Schmidt, Dominic ; Flor, Peter J. ; Uschold-Schmidt, Nicole



Abstract

Chronic stress-related psychiatric conditions and comorbid somatic pathologies are an enormous public health concern in modern society. The etiology of these disorders is complex, with stressors holding a chronic and psychosocial component representing the most acknowledged risk factor. During the last decades, research on the metabotropic glutamate receptor (mGlu) system advanced dramatically ...

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