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Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide

Hu, Zhongshuang, Murakami, Taisuke, Tamura, Hiroshi, Reich, Johannes, Kuwahara-Arai, Kyoko, Iba, Toshiaki, Tabe, Yoko and Nagaoka, Isao (2017) Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide. International Journal of Molecular Medicine 39 (3), pp. 549-558.

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Other URL: http://doi.org/10.3892/ijmm.2017.2870


Upon exposure to invading microorganisms, neutrophils undergo NETosis, a recently identified type of programmed cell death, and release neutrophil extracellular traps (NETs). NETs are described as an antimicrobial mechanism, based on the fact that NEls can trap microorganisms and exhibit bactericidal activity through the action of NET-associated components. In contrast, the components of NETs ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie
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Keywords:CELL-DEATH; SERINE PROTEASES; SEPTIC SHOCK; SEPSIS; INFLAMMATION; INTERLEUKIN-1-BETA; ACTIVATION; APOPTOSIS; STIMULATION; MECHANISMS; macrophage; neutrophil extracellular traps; IL-1 beta; lipopolysaccharide; NETosis; damage-associated molecular pattern molecules
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38641
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